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A Functional Screen for Regulatory Elements that Improve Retroviral Vector Gene Expression

Recombinant retroviruses constitute the most common class of gene delivery vectors used in hematopoietic cell-based gene therapy. However, the use of these vectors can be limited by inadequate levels of transgene expression, often mediated by expression variegation and vector silencing due to chromo...

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Detalles Bibliográficos
Main Authors: Groth, Amy C., Emery, David W.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993826/
https://ncbi.nlm.nih.gov/pubmed/20846887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2010.08.005
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