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Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes

Histone deacetylase inhibitors represent a new class of anticancer therapeutics and the expectation is that they will be most effective when used in combination with conventional cancer therapies, such as the anthracycline, doxorubicin. The dose-limiting side effect of doxorubicin is severe cardioto...

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Detalhes bibliográficos
Main Authors: Karagiannis, Tom C, Lin, Ann JE, Ververis, Katherine, Chang, Lisa, Tang, Michelle M, Okabe, Jun, El-Osta, Assam
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993796/
https://ncbi.nlm.nih.gov/pubmed/20930262
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