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Emergence of the acute-phase protein hemopexin in jawed vertebrates

When released from damaged erythrocytes free heme not only provides a source of iron for invading bacteria but is also highly toxic due to its ability to catalyze free radical formation. Hemopexin (Hx) binds free heme with very high affinity and thus protects against heme toxicity, sequesters heme f...

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Main Authors: Dooley, Helen, Buckingham, E. Bryan, Criscitiello, Michael F., Flajnik, Martin F.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993785/
https://ncbi.nlm.nih.gov/pubmed/20884052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.08.015
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