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Emergence of the acute-phase protein hemopexin in jawed vertebrates

When released from damaged erythrocytes free heme not only provides a source of iron for invading bacteria but is also highly toxic due to its ability to catalyze free radical formation. Hemopexin (Hx) binds free heme with very high affinity and thus protects against heme toxicity, sequesters heme f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dooley, Helen, Buckingham, E. Bryan, Criscitiello, Michael F., Flajnik, Martin F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993785/
https://ncbi.nlm.nih.gov/pubmed/20884052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.08.015
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