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Emergence of the acute-phase protein hemopexin in jawed vertebrates

When released from damaged erythrocytes free heme not only provides a source of iron for invading bacteria but is also highly toxic due to its ability to catalyze free radical formation. Hemopexin (Hx) binds free heme with very high affinity and thus protects against heme toxicity, sequesters heme f...

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Detalhes bibliográficos
Main Authors: Dooley, Helen, Buckingham, E. Bryan, Criscitiello, Michael F., Flajnik, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993785/
https://ncbi.nlm.nih.gov/pubmed/20884052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.08.015
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