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Hepatocyte Growth Factor Inhibits Apoptosis by the Profibrotic Factor Angiotensin II via Extracellular Signal-regulated Kinase 1/2 in Endothelial Cells and Tissue Explants

Hepatocyte growth factor (HGF), an endogenous tissue repair factor, attenuates apoptosis in many primary cell types, but the mechanism is not completely understood. Our laboratory demonstrated that angiotensin (Ang) II activates the intrinsic apoptotic pathway in primary endothelial cells (ECs) via...

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Detalles Bibliográficos
Autores principales: Lee, Young H., Marquez, Ana P., Mungunsukh, Ognoon, Day, Regina M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993751/
https://ncbi.nlm.nih.gov/pubmed/20926686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-04-0341
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