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Transforming growth factor-β1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199–dependent posttranscriptional mechanism

Hepatocyte growth factor (HGF) is a multipotent endogenous repair factor secreted primarily by mesenchymal cells with effects on cells expressing its receptor, Met. HGF promotes normal tissue regeneration and inhibits fibrotic remodeling in part by promoting proliferation and migration of endothelia...

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Autori principali: Mungunsukh, Ognoon, Day, Regina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694793/
https://ncbi.nlm.nih.gov/pubmed/23657814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-01-0017
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