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microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease

Although individuals with homozygous sickle cell disease (HbSS) share the same genetic mutation, the severity and manifestations of this disease are extremely heterogeneous. We have previously shown that the microRNA expression in normal and HbSS erythrocytes exhibit dramatic differences. In this st...

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Hlavní autoři: Sangokoya, Carolyn, Telen, Marilyn J., Chi, Jen-Tsan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993631/
https://ncbi.nlm.nih.gov/pubmed/20709907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-214817
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