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Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin

Ferroportin (FPN) is the only known cellular iron exporter in mammalian cells and plays a critical role in the maintenance of both cellular and systemic iron balance. During iron deprivation, the translation of FPN is repressed by iron regulatory proteins (IRPs), which bind to the 5′ untranslated re...

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Detalhes bibliográficos
Main Authors: Sangokoya, Carolyn, Doss, Jennifer F., Chi, Jen-Tsan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616902/
https://ncbi.nlm.nih.gov/pubmed/23593016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003408
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