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Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers

Ingestion of aristolochic acid (AA) is associated with the development of aristolochic acid nephropathy, which is characterized by chronic renal failure, tubulointerstitial fibrosis and urothelial cancer. AA may also cause a similar type of kidney fibrosis with malignant transformation of the urothe...

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Detalhes bibliográficos
Main Authors: Stiborová, Marie, Hudeček, Jiří, Frei, Eva, Schmeiser, Heinz H.
Formato: Artigo
Idioma:Inglês
Publicado em: Slovak Toxicology Society SETOX 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993473/
https://ncbi.nlm.nih.gov/pubmed/21218097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/v10102-010-0023-1
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