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Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches

This review summarizes the results found in studies investigating the enzymatic activation of two genotoxic nitro-aromatics, an environmental pollutant and carcinogen 3-nitrobenzanthrone (3-NBA) and a natural plant nephrotoxin and carcinogen aristolochic acid I (AAI), to reactive species forming cov...

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Detalhes bibliográficos
Main Authors: Stiborová, Marie, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Martínek, Václav
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100152/
https://ncbi.nlm.nih.gov/pubmed/24918288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150610271
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