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Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone

3-Aminobenzanthrone (3-ABA) is a human metabolite of carcinogenic 3-nitrobenzanthrone (3-NBA), which occurs in diesel exhaust and air pollution. Understanding which cytochrome P450 (CYP) enzymes are involved in metabolic activation and/or detoxication of this toxicant is important in the assessment...

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書誌詳細
主要な著者: Mizerovská, Jana, Dračínská, Helena, Arlt, Volker M., Hudeček, Jiří, Hodek, Petr, Schmeiser, Heinz H, Frei, Eva, Stiborová, Marie
フォーマット: Artigo
言語:Inglês
出版事項: Slovak Toxicology Society SETOX 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993481/
https://ncbi.nlm.nih.gov/pubmed/21218105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/v10102-010-0031-1
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