Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics

Restricting the cytotoxicity of anticancer agents by targeting receptors exclusively expressed on tumor cells is critical when treating infiltrative brain tumors such as glioblastoma multiforme (GBM). GBMs express an IL-13 receptor (IL13Rα2) that differs from the physiological IL4R/IL13R receptor. W...

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Detalhes bibliográficos
Main Authors: Candolfi, Marianela, Xiong, Weidong, Yagiz, Kader, Liu, Chunyan, Muhammad, A. K. M. G., Puntel, Mariana, Foulad, David, Zadmehr, Ali, Ahlzadeh, Gabrielle E., Kroeger, Kurt M., Tesarfreund, Matthew, Lee, Sharon, Debinski, Waldemar, Sareen, Dhruv, Svendsen, Clive N., Rodriguez, Ron, Lowenstein, Pedro R., Castro, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993419/
https://ncbi.nlm.nih.gov/pubmed/21030678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008261107
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