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Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models

PURPOSE: Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults. Chemotherapy with temozolomide (TMZ) significantly prolongs the survival of GBM patients. However, the 3-year survival is still ~5%. Herein we combined intratumoral administration of an adenoviral vector expres...

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Detalhes bibliográficos
Main Authors: Candolfi, Marianela, Yagiz, Kader, Wibowo, Mia, Ahlzadeh, Gabrielle E, Puntel, Mariana, Ghiasi, Homayon, Kamran, Neha, Paran, Christopher, Lowenstein, Pedro R, Castro, Maria G
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959570/
https://ncbi.nlm.nih.gov/pubmed/24501391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2140
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