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Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing

Malaria infections commonly contain multiple genetically distinct variants. Mathematical and animal models suggest that interactions among these variants have a profound impact on the emergence of drug resistance. However, methods currently used for quantifying parasite diversity in individual infec...

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Detalhes bibliográficos
Main Authors: Juliano, Jonathan J., Porter, Kimberly, Mwapasa, Victor, Sem, Rithy, Rogers, William O., Ariey, Frédéric, Wongsrichanalai, Chansuda, Read, Andrew, Meshnick, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993407/
https://ncbi.nlm.nih.gov/pubmed/21041629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007068107
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