Misclassification of Drug Failures in Plasmodium falciparum Clinical Trials in Southeast Asia

Most trials of antimalarials occur in areas where reinfections are possible. For Plasmodium falciparum, reinfections are distinguished from recrudescences by PCR analysis of 3 polymorphic genes. However, the validity of this approach has never been rigorously tested. We tested for misclassification...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Juliano, Jonathan J, Ariey, Frederic, Sem, Rithy, Tangpukdee, Noppadon, Krudsood, Srivicha, Olson, Carol, Looareesuwan, Sornchai, Rogers, William O., Wongsrichanalai, Chansuda, Meshnick, Steven R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761972/
https://ncbi.nlm.nih.gov/pubmed/19591576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600892
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