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Stepwise loading of yeast clamp revealed by ensemble and single-molecule studies

In ensemble and single-molecule experiments using the yeast proliferating cell nuclear antigen (PCNA, clamp) and replication factor C (RFC, clamp loader), we have examined the assembly of the RFC·PCNA·DNA complex and its progression to holoenzyme upon addition of polymerase δ (polδ). We obtained dat...

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Detalhes bibliográficos
Main Authors: Kumar, Ravindra, Nashine, Vishal C., Mishra, Padmaja P., Benkovic, Stephen J., Lee, Tae-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993353/
https://ncbi.nlm.nih.gov/pubmed/21041673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014139107
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