Učitavanje...
Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles
The stability, activity, and solubility of a protein sequence are determined by a delicate balance of molecular interactions in a variety of conformational states. Even so, most computational protein design methods model sequences in the context of a single native conformation. Simulations that mode...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993350/ https://ncbi.nlm.nih.gov/pubmed/21045132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012985107 |
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