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Computationally designed libraries of fluorescent proteins evaluated by preservation and diversity of function

To determine which of seven library design algorithms best introduces new protein function without destroying it altogether, seven combinatorial libraries of green fluorescent protein variants were designed and synthesized. Each was evaluated by distributions of emission intensity and color compiled...

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Detalles Bibliográficos
Main Authors: Treynor, Thomas P., Vizcarra, Christina L., Nedelcu, Daniel, Mayo, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765474/
https://ncbi.nlm.nih.gov/pubmed/17179210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609647103
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