Lack of Complement Inhibitors in the Outer Intracranial Artery Aneurysm Wall Associates with Complement Terminal Pathway Activation

Inflammation and activation of the complement system predispose to intracranial artery aneurysm (IA) rupture. Because disturbances in complement regulation may lead to increased susceptibility to complement activation and inflammation, we looked for evidence for dysregulation of the complement syste...

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Bibliographic Details
Main Authors: Tulamo, Riikka, Frösen, Juhana, Paetau, Anders, Seitsonen, Sanna, Hernesniemi, Juha, Niemelä, Mika, Järvelä, Irma, Meri, Seppo
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993312/
https://ncbi.nlm.nih.gov/pubmed/20971742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091172
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