Smooth Muscle Cell Foam Cell Formation, Apolipoproteins, and ABCA1 in Intracranial Aneurysms: Implications for Lipid Accumulation as a Promoter of Aneurysm Wall Rupture

Saccular intracranial aneurysm (sIA) aneurysm causes intracranial hemorrhages that are associated with high mortality. Lipid accumulation and chronic inflammation occur in the sIA wall. A major mechanism for lipid clearance from arteries is adenosine triphosphate-binding cassette A1 (ABCA1)-mediated...

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Bibliographic Details
Published in:J Neuropathol Exp Neurol
Main Authors: Ollikainen, Eliisa, Tulamo, Riikka, Lehti, Satu, Lee-Rueckert, Miriam, Hernesniemi, Juha, Niemelä, Mika, Ylä-Herttuala, Seppo, Kovanen, Petri T., Frösen, Juhana
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913436/
https://ncbi.nlm.nih.gov/pubmed/27283327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw041
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