Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

BACKGROUND: Rupture of a saccular intracranial aneurysm (sIA) causes an often fatal subarachnoid hemorrhage (SAH). Why some sIAs rupture remains unknown. Since sIA walls bear some histological similarities with early atherosclerotic lesions, we hypothesized that accumulation and oxidation of lipids...

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Detalhes bibliográficos
Main Authors: Frösen, Juhana, Tulamo, Riikka, Heikura, Tommi, Sammalkorpi, Sini, Niemelä, Mika, Hernesniemi, Juha, Levonen, Anna-Liisa, Hörkkö, Sohvi, Ylä-Herttuala, Seppo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893371/
https://ncbi.nlm.nih.gov/pubmed/24252658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-71
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