CD40·FasL and CTLA-4·FasL Fusion Proteins Induce Apoptosis in Malignant Cell Lines by Dual Signaling

Evolution of apoptosis resistance in both lymphoma and leukemia cells is well documented, and induction of apoptosis in malignant cells is a major goal of cancer therapy. Up-regulation of anti-apoptotic signals is one of the mechanisms whereby resistance to apoptosis emerges. We have previously desc...

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Hlavní autoři: Orbach, Ariel, Rachmilewitz, Jacob, Shani, Noam, Isenberg, Yonatan, Parnas, Miriam, Huang, Jui-Han, Tykocinski, Mark L., Dranitzki-Elhalel, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993309/
https://ncbi.nlm.nih.gov/pubmed/21088216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100301
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