CD40·FasL and CTLA-4·FasL Fusion Proteins Induce Apoptosis in Malignant Cell Lines by Dual Signaling

Evolution of apoptosis resistance in both lymphoma and leukemia cells is well documented, and induction of apoptosis in malignant cells is a major goal of cancer therapy. Up-regulation of anti-apoptotic signals is one of the mechanisms whereby resistance to apoptosis emerges. We have previously desc...

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Detalhes bibliográficos
Main Authors: Orbach, Ariel, Rachmilewitz, Jacob, Shani, Noam, Isenberg, Yonatan, Parnas, Miriam, Huang, Jui-Han, Tykocinski, Mark L., Dranitzki-Elhalel, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993309/
https://ncbi.nlm.nih.gov/pubmed/21088216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100301
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