Activation of OX40 Augments Th17 Cytokine Expression and Antigen-Specific Uveitis

Uveitis is a major and common cause of visual disability. Recent studies have shown that Th17 cells are implicated in the pathogenesis of this serious intraocular disorder. Activated T cells express an inducible costimulatory molecule called OX40, and OX40 in turn promotes the activation and prolife...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Zili, Zhong, Wenwei, Hinrichs, David, Wu, Xiumei, Weinberg, Andrew, Hall, Mark, Spencer, Doran, Wegmann, Keith, Rosenbaum, James T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993299/
https://ncbi.nlm.nih.gov/pubmed/20952591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100353
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