Glatiramer Acetate Attenuates Pro-Inflammatory T Cell Responses but Does Not Directly Protect Neurons from Inflammatory Cell Death

Glatiramer acetate (GA) is a synthetic, random, basic copolymer capable of modulating adaptive T cell responses. In animal models of various inflammatory and degenerative central nervous system disorders, GA-induced T cells cross the blood−brain barrier, secrete high levels of anti-inflammatory cyto...

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Autors principals: Herrmann, Alexander M., Göbel, Kerstin, Simon, Ole J., Melzer, Nico, Schuhmann, Michael K., Stenner, Max-Philipp, Weishaupt, Andreas, Kleinschnitz, Christoph, Bittner, Stefan, Meuth, Patrick, Stuve, Olaf, Budde, Thomas, Kieseier, Bernd C., Wiendl, Heinz, Meuth, Sven G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993293/
https://ncbi.nlm.nih.gov/pubmed/21037084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100442
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