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Innate immune detection of bacterial virulence factors via the NLRC4 inflammasome

Cytokine production by innate immune cells is initiated by signaling downstream of pattern recognition receptors, including Toll-like receptors. A subset of cytokines, including IL-1b and IL-18, require post-translational proteolysis before secretion, which provides a second mechanism of regulation....

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Autors principals: Miao, Edward A., Warren, Sarah E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993241/
https://ncbi.nlm.nih.gov/pubmed/20349122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9386-5
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