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Innate immune detection of bacterial virulence factors via the NLRC4 inflammasome
Cytokine production by innate immune cells is initiated by signaling downstream of pattern recognition receptors, including Toll-like receptors. A subset of cytokines, including IL-1b and IL-18, require post-translational proteolysis before secretion, which provides a second mechanism of regulation....
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993241/ https://ncbi.nlm.nih.gov/pubmed/20349122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9386-5 |
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