Inhibition of hydroxymethylglutaryl-coenzyme A synthase by L-659,699.
A beta-lactone isolated from Fusarium sp. has been shown to be a potent specific inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase [(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating), EC, 4.1.3.5] from rat liver. The structure of this beta-lacto...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
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| المؤلفون الرئيسيون: | , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
1987
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2890166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.21.7488 |
| الوسوم: |
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