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Novel role of endothelial BK(Ca) channels in altered vasoreactivity following hypoxia

The systemic vasculature exhibits attenuated vasoconstriction following hypobaric chronic hypoxia (CH) that is associated with endothelium-dependent vascular smooth muscle (VSM) cell hyperpolarization. We hypothesized that increased activity of endothelial cell (EC) large-conductance, calcium-activa...

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Detalhes bibliográficos
Main Authors: Hughes, Jennifer M., Riddle, Melissa A., Paffett, Michael L., Gonzalez Bosc, Laura V., Walker, Benjimen R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993202/
https://ncbi.nlm.nih.gov/pubmed/20817829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00124.2010
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