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Endothelial-dependent dilation following chronic hypoxia involves TRPV4-mediated activation of endothelial BK channels

Following chronic hypoxia (CH), the systemic vasculature exhibits blunted vasoconstriction due to endothelial-dependent hyperpolarization (EDH). Previous data demonstrate that subsequent to CH, EDH-mediated vasodilation switches from a reliance on SK(ca) and IK(ca) channels to activation of the endo...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Naik, Jay S., Walker, Benjimen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854740/
https://ncbi.nlm.nih.gov/pubmed/29380056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2112-5
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