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Endothelial-dependent dilation following chronic hypoxia involves TRPV4-mediated activation of endothelial BK channels
Following chronic hypoxia (CH), the systemic vasculature exhibits blunted vasoconstriction due to endothelial-dependent hyperpolarization (EDH). Previous data demonstrate that subsequent to CH, EDH-mediated vasodilation switches from a reliance on SK(ca) and IK(ca) channels to activation of the endo...
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| Published in: | Pflugers Arch |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Berlin Heidelberg
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854740/ https://ncbi.nlm.nih.gov/pubmed/29380056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2112-5 |
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