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Altered Protein Kinase C Regulation of Pulmonary Endothelial Store- and Receptor-Operated Ca(2+) Entry after Chronic Hypoxia
Chronic hypoxia (CH)-induced pulmonary hypertension is associated with decreased basal pulmonary artery endothelial cell (EC) Ca(2+), which correlates with reduced store-operated Ca(2+) (SOC) entry. Protein kinase C (PKC) attenuates SOC entry in ECs. Therefore, we hypothesized that PKC has a greater...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental
Therapeutics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939669/ https://ncbi.nlm.nih.gov/pubmed/20576798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.165563 |
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