Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth

Maternal food restriction (FR) during pregnancy results in intrauterine growth-restricted (IUGR) offspring that show rapid catch-up growth and develop metabolic syndrome and adult obesity. However, continued nutrient restriction during nursing delays catch-up growth and prevents development of obesi...

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Detalhes bibliográficos
Main Authors: Tosh, Darran N., Fu, Qi, Callaway, Christopher W., McKnight, Robert A., McMillen, Isabella C., Ross, Michael G., Lane, Robert H., Desai, Mina
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993166/
https://ncbi.nlm.nih.gov/pubmed/20813916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00052.2010
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