Maternal Hyperglycemia Disrupts Histone 3 Lysine 36 Trimethylation of the IGF-1 Gene

In utero environmental adaptation may predispose to lifelong morbidity. Organisms fine-tune gene expression to achieve environmental adaptation by epigenetic alterations of histone markers of gene accessibility. One example of epigenetics is how uteroplacental insufficiency-induced intrauterine grow...

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Autores principales: Zinkhan, Erin K., Fu, Qi, Wang, Yan, Yu, Xing, Callaway, Christopher W., Segar, Jeffrey L., Scholz, Thomas D., McKnight, Robert A., Joss-Moore, Lisa, Lane, Robert H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324902/
https://ncbi.nlm.nih.gov/pubmed/22548154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/930364
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