Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

Intrauterine growth restriction (IUGR) decreases serum insulin growth factor-1 (IGF-1) levels. IGF-1 is an epigenetically regulated gene that has two promoters, alternative exon 5 splicing, and multiple termination sites. The regulation of gene expression involves the whole gene, as evidenced by the...

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Bibliografiske detaljer
Main Authors: Fu, Qi, Yu, Xing, Callaway, Christopher W., Lane, Robert H., McKnight, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: The Federation of American Societies for Experimental Biology 2009
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717764/
https://ncbi.nlm.nih.gov/pubmed/19364764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-124768
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