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In vivo efficacy of a chitosan/IL-12 adjuvant system for protein-based vaccines
Vaccines based on recombinant proteins require adjuvant systems in order to generate Th1-type immune responses. We have developed a vaccine adjuvant system using a viscous chitosan solution and interleukin (IL)-12, a Th1-inducing cytokine. The chitosan solution is designed to create a depot of antig...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992965/ https://ncbi.nlm.nih.gov/pubmed/20965561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.09.058 |
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