The calmodulin inhibitor N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide directly blocks human ether à-go-go-related gene potassium channels stably expressed in human embryonic kidney 293 cells

BACKGROUND AND PURPOSE: N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide (W-7) is a well-known calmodulin inhibitor used to study calmodulin regulation of intracellular Ca(2+) signalling-related process. Here, we have determined whether W-7 would inhibit human ether [Image: see text]gene (hERG o...

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Autores principales: Zhang, Xiao-Hua, Jin, Man-Wen, Sun, Hai-Ying, Zhang, Shetuan, Li, Gui-Rong
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2010
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992901/
https://ncbi.nlm.nih.gov/pubmed/20860665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00916.x
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