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State-dependent blockade of human ether-a-go-go-related gene (hERG) K(+) channels by changrolin in stably transfected HEK293 cells
AIM: To study the effect of changrolin on the K(+) channels encoded by the human ether-a-go-go-related gene (hERG). METHODS: hERG channels were heterologously stably expressed in human embryonic kidney 293 cells, and the hERG K(+) currents were recorded using a standard whole-cell patch-clamp techni...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007811/ https://ncbi.nlm.nih.gov/pubmed/20686516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.84 |
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