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Regulation of kidney development by Shp2: An unbiased stereological analysis

Genes that regulate renal branching morphogenesis are likely to indirectly regulate nephron endowment, but few have been validated to do so in vivo. PTPN11, which encodes the nonreceptor protein tyrosine phosphatase Shp2, acts downstream of receptor tyrosine kinases to modulate the Ras-MAPK pathway...

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Detalhes bibliográficos
Main Authors: David, Frank S., Cullen-McEwen, Luise, Wu, Xue Sue, Zins, Stephen R., Lin, Julie, Bertram, John F., Neel, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992585/
https://ncbi.nlm.nih.gov/pubmed/20734316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.21236
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