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Regulation of kidney development by Shp2: An unbiased stereological analysis

Genes that regulate renal branching morphogenesis are likely to indirectly regulate nephron endowment, but few have been validated to do so in vivo. PTPN11, which encodes the nonreceptor protein tyrosine phosphatase Shp2, acts downstream of receptor tyrosine kinases to modulate the Ras-MAPK pathway...

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Détails bibliographiques
Auteurs principaux: David, Frank S., Cullen-McEwen, Luise, Wu, Xue Sue, Zins, Stephen R., Lin, Julie, Bertram, John F., Neel, Benjamin G.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992585/
https://ncbi.nlm.nih.gov/pubmed/20734316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.21236
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