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Regulation of kidney development by Shp2: An unbiased stereological analysis

Genes that regulate renal branching morphogenesis are likely to indirectly regulate nephron endowment, but few have been validated to do so in vivo. PTPN11, which encodes the nonreceptor protein tyrosine phosphatase Shp2, acts downstream of receptor tyrosine kinases to modulate the Ras-MAPK pathway...

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Autori principali: David, Frank S., Cullen-McEwen, Luise, Wu, Xue Sue, Zins, Stephen R., Lin, Julie, Bertram, John F., Neel, Benjamin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992585/
https://ncbi.nlm.nih.gov/pubmed/20734316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.21236
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