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Amyloid-β Peptide Is a Substrate of the Human 20S Proteasome
[Image: see text] Intraneuronal accumulation of ubiquitin conjugates is a pathological feature of neurodegenerative disorders such as Alzheimer’s disease (AD). Previous reports propose that accumulation of ubiquitinated species in AD is a result of inhibition of proteasomal activity by amyloid-β (Aβ...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2010
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992454/ https://ncbi.nlm.nih.gov/pubmed/21116456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100067e |
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