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Human β-Synuclein Rendered Fibrillogenic by Designed Mutations
Filamentous inclusions made of α-synuclein are found in nerve cells and glial cells in a number of human neurodegenerative diseases, including Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. The assembly and spreading of these inclusions are likely to play an important rol...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992288/ https://ncbi.nlm.nih.gov/pubmed/20833719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.160721 |
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