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Human β-Synuclein Rendered Fibrillogenic by Designed Mutations

Filamentous inclusions made of α-synuclein are found in nerve cells and glial cells in a number of human neurodegenerative diseases, including Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. The assembly and spreading of these inclusions are likely to play an important rol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zibaee, Shahin, Fraser, Graham, Jakes, Ross, Owen, David, Serpell, Louise C., Crowther, R. Anthony, Goedert, Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992288/
https://ncbi.nlm.nih.gov/pubmed/20833719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.160721
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