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Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

Src homology 2 (SH2) domains are mostly found in multicellular organisms where they recognize phosphotyrosine-containing signaling proteins. Spt6, a conserved transcription factor and putative histone chaperone, contains a C-terminal SH2 domain conserved from yeast to human. In mammals, this SH2 dom...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Diebold, Marie-Laure, Loeliger, Erin, Koch, Michael, Winston, Fred, Cavarelli, Jean, Romier, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992272/
https://ncbi.nlm.nih.gov/pubmed/20926373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146696
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