The Ecto-enzyme CD38 Is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Synthase That Couples Receptor Activation to Ca(2+) Mobilization from Lysosomes in Pancreatic Acinar Cells

Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most potent Ca(2+)-mobilizing intracellular messenger and is linked to a variety of stimuli and cell surface receptors. However, the enzyme responsible for endogenous NAADP synthesis in vivo is unknown, and it has been proposed that anothe...

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מידע ביבליוגרפי
Main Authors: Cosker, François, Cheviron, Nathalie, Yamasaki, Michiko, Menteyne, Alexis, Lund, Frances E., Moutin, Marie-Jo, Galione, Antony, Cancela, Jose-Manuel
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
Signal Transduction
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992259/
https://ncbi.nlm.nih.gov/pubmed/20870729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125864
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