ACE inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction

RATIONALE: Monocytes recruited to ischemic myocardium originate from a reservoir in the spleen, and the release from their splenic niche relies on angiotensin-II (Ang-II) signaling. OBJECTIVE: Since monocytes are centrally involved in tissue repair after ischemia, we here hypothesized that early ACE...

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Bibliografiske detaljer
Main Authors: Leuschner, Florian, Panizzi, Peter, Chico-Calero, Isabel, Lee, Won Woo, Ueno, Takuya, Cortez-Retamozo, Virna, Waterman, Peter, Gorbatov, Rostic, Marinelli, Brett, Iwamoto, Yoshiko, Chudnovskiy, Aleksey, Figueiredo, Jose-Luiz, Sosnovik, David E., Pittet, Mikael J., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992104/
https://ncbi.nlm.nih.gov/pubmed/20930148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.227454
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