A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation

The overexpression of cyclooxygenase (COX)-2 is a frequent event in squamous cell carcinomas of the head and neck (HNSCC), and non-steroidal anti-inflammatory drugs, which are potent inhibitors of COX-1 and COX-2, exert chemopreventive effects on HNSCC cancer development. COX-2 promotes the release...

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Main Authors: ABRAHAO, Aline Correa, CASTILHO, Rogerio M., SQUARIZE, Cristiane H., MOLINOLO, Alfredo A., dos SANTOS-PINTO, Decio, GUTKIND, J. Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991505/
https://ncbi.nlm.nih.gov/pubmed/20951077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2010.09.005
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