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Inhibition of Histone Deacetylase Impacts Cancer Stem Cells and Induces Epithelial-Mesenchyme Transition of Head and Neck Cancer

The genome is organized and packed into the nucleus through interactions with core histone proteins. Emerging evidence suggests that tumors are highly responsive to epigenetic alterations that induce chromatin-based events and dynamically influence tumor behavior. We examined chromatin organization...

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Detalhes bibliográficos
Main Authors: Giudice, Fernanda S., Pinto, Decio S., Nör, Jacques E., Squarize, Cristiane H., Castilho, Rogerio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603970/
https://ncbi.nlm.nih.gov/pubmed/23527004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058672
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