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Inhibition of Histone Deacetylase Impacts Cancer Stem Cells and Induces Epithelial-Mesenchyme Transition of Head and Neck Cancer

The genome is organized and packed into the nucleus through interactions with core histone proteins. Emerging evidence suggests that tumors are highly responsive to epigenetic alterations that induce chromatin-based events and dynamically influence tumor behavior. We examined chromatin organization...

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Bibliografski detalji
Glavni autori: Giudice, Fernanda S., Pinto, Decio S., Nör, Jacques E., Squarize, Cristiane H., Castilho, Rogerio M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603970/
https://ncbi.nlm.nih.gov/pubmed/23527004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058672
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