PTEN Deficiency Contributes to the Development and Progression of Head and Neck Cancer

The sequencing of the head and neck cancer has provided a blueprint of the most frequent genetic alterations in this cancer type. They include inactivating mutations in Notch, p53, and p16(ink4a) tumor suppressor genes, in addition to nonoverlapping activating mutations of the PIK3CA and RAS oncogen...

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Detalhes bibliográficos
Main Authors: Squarize, Cristiane H, Castilho, Rogerio M, Abrahao, Aline C, Molinolo, Alfredo, Lingen, Mark W, Gutkind, J Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638349/
https://ncbi.nlm.nih.gov/pubmed/23633918
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