PTEN Deficiency Contributes to the Development and Progression of Head and Neck Cancer

The sequencing of the head and neck cancer has provided a blueprint of the most frequent genetic alterations in this cancer type. They include inactivating mutations in Notch, p53, and p16(ink4a) tumor suppressor genes, in addition to nonoverlapping activating mutations of the PIK3CA and RAS oncogen...

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Bibliografiske detaljer
Main Authors: Squarize, Cristiane H, Castilho, Rogerio M, Abrahao, Aline C, Molinolo, Alfredo, Lingen, Mark W, Gutkind, J Silvio
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638349/
https://ncbi.nlm.nih.gov/pubmed/23633918
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