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Cellular Inhibitor of Apoptosis 1 (cIAP-1) Degradation by Caspase 8 During TNF-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis
TNF-related apoptosis-inducing ligand (TRAIL) is a potential chemotherapeutic agent with high selectivity for malignant cells. Many tumors, however, are resistant to TRAIL cytotoxicity. Although cellular inhibitor of apoptosis 1 and 2 (cIAP-1 and -2) are often over-expressed in cancers, their role i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991414/ https://ncbi.nlm.nih.gov/pubmed/20951133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.10.005 |
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